Monthly Archives: September 2012

Towards quantitative metagenomics of wild viruses and other ultra-low concentration DNA samples: a rigorous assessment and optimization of the linker amplification method

September 2012 Authors: Melissa B. Duhaime, Li Deng, Bonnie T. Poulos, and Matthew B. Sullivan Info: A study of most reproducible and sample-efficient methods for sequencing meta-genomic samples with very low abundance samples (20 L ocean water ->1 pg to … more »

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Transcriptional Amplification in Tumor Cells with Elevated c-Myc

September 2012 Authors: Charles Y. Lin, Jakob Loven,Peter B. Rahl, Ronald M. Paranal, Christopher B. Burge, James E. Bradner, Tong Ihn Lee, and Richard A. Young Info: This high impact study completely revises knowledge on how c-myc gene is involved … more »

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What’s in a Name?

We frequently get asked about the name “Pippin”, and why we’ve chosen it for our products. We thought it would be fun to see if the moniker has been also adapted in other fields of use — this is what … more »

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Scientists Use Pippin in Sequencing Effort for Seven Cholera Isolates

A paper published this month in BMC Genomics discusses findings from a collaborative project to sequence cholera samples linked to the 2010 outbreak in Haiti — and we’re pleased to report that the Pippin platform from Sage Science was used … more »

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High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic

September 2012 Authors: Rachel Sealfon, Stephen Gire, Crystal Ellis, Stephen Calderwood, Firdausi Qadri, Lisa Hensley, Manolis Kellis, Edward T Ryan, Regina C LaRocque, Jason B Harris, Pardis C Sabeti Info: Study performs high-depth NGS on V. cholerae strains from Haiti … more »

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Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

September 2012 Authors: Marcin Imielinski et al. Info: A landmark study of lung cancer genomes with 183 tumor/normal genomes compared. Sequencing was carried out mainly by the Broad Illumina Platform (8 Pippins in production). The Pippin Prep is cited in … more »

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Band Capture with Midori Green on the BluePippin

Our band capture cassettes, for use on the BluePippin, are designed to automatically collect a band or fragment of DNA from a sample and remove unwanted DNA and/or primer artifacts. We’ve provided users with some flexibility to manipulate the capture … more »

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BluePippin “Mid-Range” Size Selection: 18-27 kb

We’re pleased to be shipping our Mid-Range size selection cassette (BMF7510) for the BluePippin. While our Low-Range cassette (BLF7510, 1kb-10kb) works for many mate-pair library construction protocols, we’ve been hearing from our customers that there is interest in creating larger … more »

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