Tag Archives: PippinHT

Assembly and annotation of a draft genome sequence for Glycine latifolia, a perennial wild relative of soybean

April 2018 Authors: Qiong Liu, Sungyul Chang, Glen Hartman, and Leslie Domier Info: At the University of Illinois, scientists sequenced a wild perennial relative of the soybean plant, producing a 939 Mb draft assembly using linked reads from a single … more »

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Transmission of microRNA antimiRs to mouse offspring via the maternal-placental-fetal unit

March 2018 Authors: Jonas Hönig, Ivana Mižíková, Claudio Nardiello, David Emanuel Surate Solaligue, et al. Info: In Germany, researchers delivered microRNA inhibitors to pregnant mice, finding that the antimiRs were then detectable in offspring, where they caused fewer off-target effects … more »

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New Protocol: Analyze Small Extracellular RNAs with PippinHT

Good protocols are the currency of any lab. If your research involves working with small RNAs, be sure to check out this carefully documented protocol published in Extracellular RNA, part of Springer Nature’s Methods in Molecular Biology book series. The protocol … more »

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Improving saliva shotgun metagenomics by chemical host DNA depletion

February 2018 Authors: Clarisse Marotz, Jon Sanders, Cristal Zuniga, Livia Zaramela, Rob Knight, and Karsten Zengler Info: Scientists from the University of California, San Diego, developed and evaluated a new protocol for enriching microbial DNA collected from fresh and frozen … more »

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Study protocol: rationale and design of the community-based prospective cohort study of kidney function and diabetes in rural New Mexico, the COMPASS study

February 2018 Authors: Antonin Jaros, Hafiz Sroya, Venita Wolfe, Vikas Ghai, et al. Info: Scientists report design and launch of the COMPASS study, a prospective, longitudinal cohort in rural New Mexico aimed at better understanding diabetic chronic kidney disease and … more »

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Ribonuclease Inhibitor 1 regulates erythropoiesis by controlling GATA1 translation

February 2018 Authors: Vijaykumar Chennupati, Diogo Veiga, Kendle Maslowski, Nicola Andina, et al. Info: Scientists studying the ribonuclease inhibitor protein found that it controls translation of GATA1 and thereby regulates erythropoiesis, helping to explain anemia-associated diseases caused by mutations in … more »

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Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer

February 2018 Authors: Shusuke Toden, Preethi Ravindranathan, Jinghua Gu, Jacob Cardenas, Madelaine Yuchang & Ajay Goel Info: Scientists from Baylor University Medical Center studied the chemoprotective role of oligomeric proanthocyanidins, finding that they inhibited cellular proliferation and spurred apoptosis. RNA … more »

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Identification of a precursor processing protease from the spider Cupiennius saleiessential for venom neurotoxin maturation

February 2018 Authors: Nicolas Langenegger, Dominique Koua, Stefan Schürch, Manfred Heller, Wolfgang Nentwig and Lucia Kuhn-Nentwig Info: In this paper, scientists from the University of Bern and collaborators report the identification and purification of a protease that’s an important neurotoxin … more »

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A Look Back at 2017

As we start to make lists of New Year’s resolutions (with bets on how long they’ll last), it’s the perfect time for a moment to absorb the themes and highlights of 2017. In our corner of the world, that means … more »

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Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

December 2017 Authors: Ruben Boers, Joachim Boers, Bas de Hoon, Christel Kockx, et al. Info: Scientists at Erasmus Medical Center determined that analysis of genome-wide methylation is challenging when fragment sizes are too small and that better epigenetic results are … more »

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