Monthly Archives: October 2014

BluePippin Optimized for Illumina’s Moleculo Kit

As Sage Science blog readers know, BluePippin is used throughout the genomics community for size-selecting larger fragments — we’ve gotten lots of attention for how well the tool performs with extremely long reads from the Pacific Biosciences sequencer, for example. … more »

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7,000 Handshakes Later, We Bid Adieu to ASHG

The Sage Science crew is back in Boston, ready for some much-needed rest after a fun-filled ASHG 2014. We didn’t meet all 7,000+ attendees at the event, but we certainly gave it our best shot! Many thanks to all of … more »

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At ASHG, the Big Picture Is Big Studies

Here at ASHG 2014, we’ve taken a moment to step back and look at the bigger picture for the narrative tying together the top-notch presentations, stellar posters, and frenetic exhibit hall breaks. What we’re seeing is that, several years after … more »

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Dispatches from San Diego: ASHG 2014

The first day of ASHG 2014 has been a whirlwind of great science, engaging talks, and (of course) the inevitable zany environment of the exhibit hall. Attendees are swarming Oxford Nanopore’s booth, where representatives are apparently sequencing samples on-site. Last … more »

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ASHG 2014: See You in San Diego!

We can’t wait for the annual conference for the American Society of Human Genetics in San Diego this weekend! Five days of back-to-back scientific sessions, 6,500 attendees, countless parties — it’s a great opportunity to geek out on genomics. While … more »

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Illumina Workflow: Pippin for Improved Assembly Accuracy

As we’ve seen throughout this blog series, Sage customers are conducting all sorts of great experiments pairing their Pippin size selection instruments with Illumina sequencers. Today we look at the final topic in this thread: boosting assembly accuracy with precise … more »

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Cancer Genomics Crowd in Boston for Beyond the Genome Meeting

We’re gearing up for this week’s Beyond the Genome conference, to be held at Harvard Medical School here in Boston. This year’s event, hosted by Genome Medicine and Genome Biology, will focus on cancer genomics, therapies, and bioinformatics. A timely … more »

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New Resources: App Notes for Mate-Pair and Long-Read Sequencing with BluePippin

We’ve got some new application notes to share that will be particularly handy for BluePippin customers running mate-pair libraries or sequencing with the Pacific Biosciences platform. Many thanks to our distribution partner, Nippon Genetics, for making this great information available … more »

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Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae

September 2014 Authors: Sean Conlan, Pamela J. Thomas, Clayton Deming, Morgan Park, Anna F. Lau, John P. Dekker, Evan S. Snitkin, Tyson A. Clark, Khai Luong, Yi Song, Yu-Chih Tsai, Matthew Boitano, Jyoti Dayal, Shelise Y. Brooks, Brian Schmidt, Alice … more »

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Placental miR-1301 is dysregulated in early-onset preeclampsia and inversely correlated with maternal circulating leptin

September 2014 Authors: M.S. Weedon-Fekjær, Y. Sheng, M. Sugulle, G.M. Johnsen, F. Herse, C.W. Redman, R. Lyle, R. Dechend, A.C. Staff Info: Scientists from Norway, the UK, and Germany used sequenced small RNAs in placenta from patients with and without … more »

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