Monthly Archives: January 2016

A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling

January 2016 Authors: Rosalinda D’Amore, Umer Zeeshan Ijaz, Melanie Schirmer, John G. Kenny, Richard Gregory, Alistair C. Darby, Migun Shakya, Mircea Podar, Christopher Quince and Neil Hall Info: Scientists used synthetic metagenomic communities to evaluate the performance of different sequencing … more »

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Harnessing the power of RADseq for ecological and evolutionary genomics

January 2016 Authors: Kimberly R. Andrews, Jeffrey M. Good, Michael R. Miller, Gordon Luikart and Paul A. Hohenlohe Info: In this protocol review, scientists examine several approaches to restriction site-associated DNA sequencing and present their findings on how to choose … more »

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ChIA-PET Study Demonstrates Effect of Genome Folding on Gene Expression

For a recent publication in Cell, scientists used the SageELF whole-sample fractionation platform to perform size selection prior to cDNA sequencing on the PacBio system. The Iso-Seq method allows PacBio users to generate full-length transcripts, and SageELF makes it easier … more »

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This PAG Was One for the Birds (and Other Organisms, Too)

The 24th annual PAG meeting ended earlier this week, and we thoroughly enjoyed ourselves — as did just about every other attendee we encountered. The avian genomics community one-upped everyone else by going on bird-watching excursions and tweeting photos of … more »

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

December 2015 Authors: Zhonghui Tang, Oscar Junhong Luo, Xingwang Li, et al. Info: Scientists from the Jackson Lab and many collaborating institutes used the ChIA-PET strategy with other data sets to understand how genome organization affects transcription in human cells. … more »

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On Our Way to the 24th Annual PAG Conference

We’re heading to San Diego this weekend, braving historic rain and mudslides for our favorite agbio conference: the International Plant & Animal Genome meeting, held January 9-13. Each year, thousands of scientists descend on the Town and Country hotel to … more »

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