Author Archives: Alex

Ingestible Osmotic Pill for In‐vivo Sampling of Gut Microbiome

July 2019 Authors: Hojatollah Rezaei Nejad, Bruno C. M. Oliveira, Aydin Sadeqi, Amin Dehkharghani, Ivanela Kondova Jan A. M. Langermans, Jeffrey S. Guasto, Saul Tzipori, Giovanni Widmer, Sameer R. Sonkusale Info: From Engineering and Nano Labs at Tufts University, and … more »

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Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome

June 2019 Authors: De Coster Wouter, De Rijk Peter, De Roeck Arne, De Pooter Tim, D’Hert Svenn, Strazisar Mojca, Kristel Sleegers and Van Broeckhoven Christine Info: Researchers from VIB Center for Molecular Neurology, Antwerp Belgium and University of Antwerp assess … more »

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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the differentiation of embryonic stem cells towards pancreatic lineage and pancreatic beta cell function

May 2019 Authors: John A. Kubi, Andy C.H. Chen, Sze Wan Fong, Keng Po Lai, Chris K.C. Wong, William S.B. Yeung, Kai Fai Lee, Yin Lau Lee Info: From the University of Hong Kong and Hong Kong Baptist University, this … more »

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Sage Science Receives $1.8M Grant from NHGRI to Automate the HLS-CATCH Targeted DNA Sample Preparation Method

BEVERLY, Mass. — May 21, 2019— Sage Science, a developer of products for improving sample preparation processes in life science applications, today announced the award of $1.8M from the National Human Genome Research Institute. The grant funds a two-year program … more »

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Systematic sequencing of chloroplast transcript termini from Arabidopsis thaliana reveals >200 transcription initiation sites and the extensive imprints of RNA-binding proteins and secondary structures

April 2019 Authors: Benoît Castandet, Arnaud Germain, Amber M. Hotto, and David B. Stern Info: Researchers present a protocol called Terminome-Seq that they developed to catalog RNA transcript termini in chloroplast DNA of Arabidopsis thaliana. RNA-seq libraries are prepared for … more »

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Museum epigenomics: characterizing cytosine methylation in historic museum specimens

April 2019 Authors: Tricia L. Rubi, L. Lacey Knowles, Ben Dantzer Info: In this preprint, researchers developed method the study epigenetic markers on historically preserved deer mouse specimens using ddRAD-seq and bisulfite sequencing. The oldest group of specimens was 76 … more »

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Comparison of RNA isolation and library preparation methods for small RNA sequencing of canine biofluids

Authors: Candice P. Chu, Mary B. Nabity Info: From the Department of Veterinary Pathobiology at Texas A&M, this study evaluates best practices for small RNA sequencing from canine biofluid samples (serum and urine). The study compares RNA-seq results after using … more »

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Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome

March 2019 Authors: Jared P. Steranka, Zuojian Tang, Mark Grivainis, Cheng Ran Lisa Huang, Lindsay M. Payer, Fernanda O. R. Rego, Thiago Luiz Araujo Miller, Pedro A. F. Galante, Sitharam Ramaswami, Adriana Heguy, David Fenyö, Jef D. Boeke & Kathleen … more »

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Identification of whole blood mRNA and microRNA biomarkers of tissue damage and immune function resulting from amphetamine exposure or heat stroke in adult male rats

February 2019 Authors: Luısa Camacho, Camila S. Silva, Joseph P. Hanig, Robert P. Schleimer, Nysia I. George, John F. Bowyer Info: A report from the USDA and others evaluate the effect of amphetamine and methamphetamine toxicity on immune systems and … more »

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AGBT 2019 Re-Cap

AGBT 2019 was a smashing success this year. Featuring a triumphant return to Marco Island FL with postcard perfect weather, the science was (as usual) top-notch. The renovated Marriott greatly upgraded its conference facilities and added an attractive new tower … more »

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