Tag Archives: DNA Sequencing

A draft genome of the brown alga, Cladosiphon okamuranus, S-strain: a platform for future studies of ‘mozuku’ biology

August 2016 Authors: Koki Nishitsuji, Asuka Arimoto, Kenji Iwai, Yusuke Sudo, Kanako Hisata, Manabu Fujie, Nana Arakaki, Tetsuo Kushiro, Teruko Konishi, Chuya Shinzato, Noriyuki Satoh and Eiichi Shoguchi Info: Scientists from Japan sequenced the genome of Cladosiphon okamuranus, an edible … more »

Posted in Citation | Tagged , , , , | Comments Off on A draft genome of the brown alga, Cladosiphon okamuranus, S-strain: a platform for future studies of ‘mozuku’ biology

DSBCapture: in situ capture and sequencing of DNA breaks

August 2016 Authors: Stefanie V Lensing, Giovanni Marsico, Robert Hänsel-Hertsch, Enid Y Lam, David Tannahill & Shankar Balasubramanian Info: Scientists at Cancer Research UK developed and validated a new sequencing-based protocol to spot double-stranded DNA breaks in situ; these regions … more »

Posted in Citation | Tagged , , , , | Comments Off on DSBCapture: in situ capture and sequencing of DNA breaks

Comparative genomics and transcriptomics of Pichia pastoris

August 2016 Authors: Kerry R. Love, Kartik A. Shah, Charles A. Whittaker, Jie Wu, M. Catherine Bartlett, Duanduan Ma, Rachel L. Leeson, Margaret Priest, Jonathan Borowsky, Sarah K. Young and J. Christopher Love Info: To provide a foundation for engineering … more »

Posted in Citation | Tagged , , , | Comments Off on Comparative genomics and transcriptomics of Pichia pastoris

Comparison of Sample Preparation Methods Used for the Next-Generation Sequencing of Mycobacterium tuberculosis

February 2016 Authors: Andrea D. Tyler, Sara Christianson, Natalie C. Knox, Philip Mabon, Joyce Wolfe, Gary Van Domselaar, Morag R. Graham, and Meenu K. Sharma Info: In this PLoS One publication, scientists in Manitoba compare the quality of libraries constructed … more »

Posted in Citation | Tagged , , , | Comments Off on Comparison of Sample Preparation Methods Used for the Next-Generation Sequencing of Mycobacterium tuberculosis

Sage Science Launches High-Throughput DNA Sizing Platform for NGS Workflow

BEVERLY, Mass. — November 11, 2014 — Sage Science, a developer of life science products for improving sample preparation processes in molecular biology applications, today introduced the PippinHT, a high-throughput version of the popular Pippin line of automated DNA size … more »

Posted in News, News, Press Release | Tagged , | Comments Off on Sage Science Launches High-Throughput DNA Sizing Platform for NGS Workflow

Proteomics & Long-Read Sequencing, Together in Baltimore

Next week we’ll be heading south to Baltimore, home of the Orioles and Ravens, for two special events: the annual conference of the American Society for Mass Spectrometry and the Pacific Biosciences user group meeting. The 62nd annual ASMS, to … more »

Posted in Blog | Tagged , , , , , , | Comments Off on Proteomics & Long-Read Sequencing, Together in Baltimore

Genome Editing Shows Potential for Shrinking Repeat Expansions

Several diseases, many of them involving neurological symptoms, have been linked to expansions of trinucleotide repeat sequences. These repeat expansion disorders include Fragile X syndrome, Huntington’s disease, and various forms of epilepsy and ataxia. In Fragile X, for example, a … more »

Posted in Blog | Tagged , , | Comments Off on Genome Editing Shows Potential for Shrinking Repeat Expansions

Quality control of next-generation sequencing data without a reference

May 2014 Authors: Urmi H Trivedi, Timothée Cézard, Stephen Bridgett, Anna Montazam, Jenna Nichols, Mark Blaxter, and Karim Gharbi Info: In this paper published in Frontiers in Genetics, scientists at the University of Edinburgh show that it is possible to … more »

Posted in Citation | Tagged , , | Comments Off on Quality control of next-generation sequencing data without a reference

Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast

April 2014 Authors: Guy-Franck Richard, David Viterbo, Varun Khanna, Valentine Mosbach, Lauriane Castelain, and Bernard Dujon Info: Researchers in France used a TALEN to introduce a double-strand break in a CAG/CCTG repeat in yeast cells, finding that doing so deleted … more »

Posted in Citation | Tagged , , | Comments Off on Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast

The emerging biofuel crop Camelina sativa retains a highly undifferentiated hexaploid genome structure

April 2014 Authors: Sateesh Kagale, Chushin Koh, John Nixon, Venkatesh Bollina, Wayne E. Clarke, Reetu Tuteja, Charles Spillane, Stephen J. Robinson, Matthew G. Links, Carling Clarke, Erin E. Higgins, Terry Huebert, Andrew G. Sharpe & Isobel A.P. Parkin Info: Scientists … more »

Posted in Citation | Tagged , , | Comments Off on The emerging biofuel crop Camelina sativa retains a highly undifferentiated hexaploid genome structure