Tag Archives: DNA Sequencing

A first genetic map of date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms

April 2014 Authors: Lisa S Mathew, Manuel Spannagl, Ameena Al-Malki, Binu George, Maria F Torres, Eman K Al-Dous, Eman K Al-Azwani, Emad Hussein, Sweety Mathew, Klaus FX Mayer, Yasmin Ali Mohamoud, Karsten Suhre and Joel A Malek Info: The first … more »

Posted in Citation | Tagged , , , | Comments Off on A first genetic map of date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms

DNA methylation is required for the control of stem cell differentiation in the small intestine

March 2014 Authors: Karyn L. Sheaffer, Rinho Kim, Reina Aoki, Ellen N. Elliott, Jonathan Schug, Lukas Burger, Dirk Schubeler, and Klaus H. Kaestner Info: Scientists in Switzerland and Pennsylvania sought to understand the role of methylation in stem cell-directed regeneration … more »

Posted in Citation | Tagged , , | Comments Off on DNA methylation is required for the control of stem cell differentiation in the small intestine

Comparison of single-molecule sequencing and hybrid approaches for finishing the genome of Clostridium autoethanogenum and analysis of CRISPR systems in industrial relevant Clostridia

March 2014 Authors: Steven D Brown, Shilpa Nagaraju, Sagar Utturkar, Sashini De Tissera, Simón Segovia, Wayne Mitchell, Miriam L Land, Asela Dassanayake, and Michael Köpke Info: Scientists generated a closed, high-quality genome sequence for a Clostridium autoethanogenum strain capable of … more »

Posted in Citation | Tagged , , | Comments Off on Comparison of single-molecule sequencing and hybrid approaches for finishing the genome of Clostridium autoethanogenum and analysis of CRISPR systems in industrial relevant Clostridia

Comprehensive profiling of the vaginal microbiome in HIV positive women using massive parallel semiconductor sequencing

March 2014 Authors: Adam Ameur, Tracy L. Meiring, Ignas Bunikis, Susana Ha¨ggqvist, Cecilia Lindau, Julia Hedlund Lindberg, Inger Gustavsson, Zizipho Z. A. Mbulawa, Anna-Lise Williamson and Ulf Gyllensten Info: Researchers at Uppsala University, Sweden, along with the University of Cape … more »

Posted in Citation | Tagged , , | Comments Off on Comprehensive profiling of the vaginal microbiome in HIV positive women using massive parallel semiconductor sequencing

At AGBT, a Big Day for Blue!

Our BluePippin instrument got a little celebrity treatment at AGBT today. Several PacBio users who spoke during the plenary and evening sessions noted that BluePippin is an essential part of their SMRT Sequencing pipeline. We were especially flattered to get … more »

Posted in Blog | Tagged , , , , , | Comments Off on At AGBT, a Big Day for Blue!

As Sequencing Techs Mature, Scientists Look to Sample Prep for Improvements

We come to AGBT year after year because it is the place for new advances in DNA sequencing. But this year we’re hearing more and more about a cause that has special importance to us: sample prep. In the first … more »

Posted in Blog | Tagged , , , , | Comments Off on As Sequencing Techs Mature, Scientists Look to Sample Prep for Improvements

Sage Science Launches Unique Tool to Maximize Value of DNA and Protein Samples

BEVERLY, Mass. — February 12, 2014 — Sage Science, a developer of products for improving sample preparation processes in life science applications, today announced the release of its new SageELF technology for DNA and protein fractionation. This sample prep instrument … more »

Posted in News, News, Press Release | Tagged , , | Comments Off on Sage Science Launches Unique Tool to Maximize Value of DNA and Protein Samples

Transcriptome Analysis in Venom Gland of the Predatory Giant Ant Dinoponera quadriceps: Insights into the Polypeptide Toxin Arsenal of Hymenopterans

January 2014 Authors: Alba F. C. Torres, Chen Huang, Cheong-Meng Chong, Siu Wai Leung, Alvaro R. B. Prieto-da-Silva, Alexandre Havt, Yves P. Quinet, Alice M. C. Martins, Simon M. Y. Lee, and Gandhi Radis-Baptista Info: Scientists from Brazil and Macao … more »

Posted in Citation | Tagged , , | Comments Off on Transcriptome Analysis in Venom Gland of the Predatory Giant Ant Dinoponera quadriceps: Insights into the Polypeptide Toxin Arsenal of Hymenopterans

Mitochondrial Sequence Variation in African-American Primary Open-Angle Glaucoma Patients

October 2013 Authors: David W. Collins, Harini V. Gudiseva, Benjamin T. Trachtman, Matthew Jerrehian, Thomasine Gorry, William T. Merritt III, Allison L. Rhodes, Prithvi S. Sankar, Meredith Regina, Eydie Miller-Ellis, Joan M. O’Brien Info: Researchers at the University of Pennsylvania … more »

Posted in Citation | Tagged , , | Comments Off on Mitochondrial Sequence Variation in African-American Primary Open-Angle Glaucoma Patients

Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors

October 2013 Authors: Michelle Schorn, Judith Zettler, Joseph P. Noel, Pieter C. Dorrestein, Bradley S. Moore, and Leonard Kaysser Info: Scientists from California and Germany teamed up to study genes that encode for the biosynthesis of an important component of … more »

Posted in Citation | Tagged , , | Comments Off on Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors