Tag Archives: HiSeq

Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

July 2017 Authors: Justin Quiles, Madhusudhanan Narasimhan, Gobinath Shanmugam, Brett Milash, John Hoidal, and Namakkal Rajasekaran Info: Scientists from the University of Alabama at Birmingham and other institutions studied a gene previously associated with oxidative stress, analyzing differential expression in … more »

Posted in Citation | Tagged , , | Comments Off on Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

March 2017 Authors: Warren Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, et al. Info: Researchers at McGill University and collaborating institutions used ChIP-seq to elucidate the effects of epigenetics and phenotype across the human genome. They analyzed more than 900 … more »

Posted in Citation | Tagged , , | Comments Off on Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Asymmetric subgenome selection and cis-regulatory divergence during cotton domestication

March 2017 Authors: Maojun Wang, Lili Tu, Min Lin, Zhongxu Lin, et al. Info: Scientists from China and the UK scanned the genomes of 352 varieties of cotton, both wild and domestic, to map variants associated with crop domestication throughout … more »

Posted in Citation | Tagged , | Comments Off on Asymmetric subgenome selection and cis-regulatory divergence during cotton domestication

Small genomic insertions form enhancers that misregulate oncogenes

February 2017 Authors: Brian J. Abraham, Denes Hnisz, Abraham S. Weintraub, Nicholas Kwiatkowski, et al. Info: In this paper, scientists report using ChIP-seq to better understand the role of non-coding somatic insertions in tumorigenesis. They identified enhancer-associated small insertions, often … more »

Posted in Citation | Tagged , , | Comments Off on Small genomic insertions form enhancers that misregulate oncogenes

Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis

February 2017 Authors: Joseph A. Karam, Rasesh Y. Parikh, Dhananjaya Nayak, David Rosenkranz and Vamsi K. Gangaraju Info: Scientists from South Carolina and Mainz, Germany, studied Hop, a co-chaperone that interacts with a piRNA in Drosophila. They found that knocking … more »

Posted in Citation | Tagged , , , | Comments Off on Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis

Defining an olfactory receptor function in airway smooth muscle cells

December 2016 Authors: William H. Aisenberg, Jessie Huang, Wanqu Zhu, Premraj Rajkumar, et al. Info: Scientists at Johns Hopkins University, Rutgers, and other institutions teamed up to study receptors in airway smooth muscle cells that appear to play a role … more »

Posted in Citation | Tagged , , | Comments Off on Defining an olfactory receptor function in airway smooth muscle cells

Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining

December 2016 Authors: Peter Ly, Levi S. Teitz, Dong H. Kim, Ofer Shoshani, Helen Skaletsky, Daniele Fachinetti, David C. Page, and Don W. Cleveland Info: Scientists report developing a strategy to examine what happens when chromosomes do not segregate properly. … more »

Posted in Citation | Tagged , | Comments Off on Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining

Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

November 2016 Authors: Eileen P Hamilton, Aurélie Kapusta, Piroska E Huvos, Shelby L Bidwell, et al. Info: A large team of scientists in Asia, Europe, and the U.S. collaborated for this study of Tetrahymena thermophile, for which they produced a complete sequence assembly. They … more »

Posted in Citation | Tagged , | Comments Off on Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

A draft genome of the brown alga, Cladosiphon okamuranus, S-strain: a platform for future studies of ‘mozuku’ biology

August 2016 Authors: Koki Nishitsuji, Asuka Arimoto, Kenji Iwai, Yusuke Sudo, Kanako Hisata, Manabu Fujie, Nana Arakaki, Tetsuo Kushiro, Teruko Konishi, Chuya Shinzato, Noriyuki Satoh and Eiichi Shoguchi Info: Scientists from Japan sequenced the genome of Cladosiphon okamuranus, an edible … more »

Posted in Citation | Tagged , , , , | Comments Off on A draft genome of the brown alga, Cladosiphon okamuranus, S-strain: a platform for future studies of ‘mozuku’ biology

Association of MicroRNAs with Antibody Response to Mycoplasma bovis in Beef Cattle

August 2016 Authors: Eduardo Casas, Guohong Cai, Larry A. Kuehn, Karen B. Register, Tara G. McDaneld, John D. Neill Info: USDA scientists performed a longitudinal study of young cows to identify microRNAs linked to a serum antibody produced after exposure … more »

Posted in Citation | Tagged , , , , | Comments Off on Association of MicroRNAs with Antibody Response to Mycoplasma bovis in Beef Cattle