Tag Archives: Pippin Prep

Significance of HLA in the development of Graves’ orbitopathy

January 2023 Authors: Magdalena Stasiak, Katarzyna Zawadzka-Starczewska, Bogusław Tymoniuk, Bartłomiej Stasiak, Andrzej Lewiński Abstract: “Graves’ disease (GD), similarly to most autoimmune disease, is triggered by environmental factors in genetically predisposed individuals. Particular HLA alleles increase or decrease GD risk. No … more »

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Optimising ddRAD sequencing for population genomic studies with ddgRADer

October 2022 Authors: Aparna Lajmi, Felix Glinka, Eyal Privman Info: In this preprint, the authors describe an online webtool that they have developed for designing ddRAD-seq experiments. This webtool assists in the recommendation of restriction enzyme pairs and size-selection criteria. … more »

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rDNA array length is a major determinant of replicative lifespan in budding yeast

April 2022 Authors: Manuel Hotz, Nathaniel H. Thayer, David G. Hendrickson, Elizabeth L. Schinski, Jun Xu, and Daniel E. Gottschling Info: The authors propose a new mechanism for aging and lifespan determination in budding yeast. The researchers “discovered a previously … more »

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Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology

April 2021 Authors: Multiple authors, the SEQC2 Oncopanel Sequencing Working Group Info: A multi-site and cross-platform evaluation of circulating tumor DNA (ctDNA) NGS assays was conducted by the SEQC2 Oncopanel Sequencing Working Group and reported on in this comprehensive study. … more »

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Identifying the true number of specimens of the extinct blue antelope (Hippotragus leucophaeus)

Jan 2021 Authors: Elisabeth Hempel, Faysal Bibi, J. Tyler Faith, James S. Brink, Daniela C. Kalthoff, Pepijn Kamminga, Johanna L. A. Paijmans, Michael V. Westbury, Michael Hofreiter & Frank E. Zachos Info: In an effort to better understand the mechanisms … more »

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Decimated little brown bats show potential for adaptive change

April 2020 Authors: Giorgia G. Auteri & L. Lacey Knowles Info: Little brown bats have experienced a 90% population decline due to fungal pathogen that causes a disease, white-nose syndrome. The authors used ddRADseq to compare surviving and non-surviving individuals. … more »

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A restriction enzyme reduced representation sequencing approach for low-cost, high-throughput metagenome profiling

April 2020 Authors: Melanie K. Hess, Suzanne J. Rowe, Tracey C. Van Stijn, Hannah M. Henry, Sharon M. Hickey, Rudiger Brauning, Alan F. McCulloch, Andrew S. Hess, Michelle R. Kirk, Sandeep Kumar, Cesar Pinares-Patiño, Sandra Kittelmann, Graham R. Wood, Peter … more »

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Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

February 2020 Authors: Phuong-Uyen C. Dinh, Dipti Paudel, Hayden Brochu, Kristen D. Popowski, M. Cyndell Gracieux, Jhon Cores, Ke Huang, M. Taylor Hensley, Erin Harrell, Adam C. Vandergriff, Arianna K. George, Raina T. Barrio, Shiqi Hu, Tyler A. Allen, Kevin … more »

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Ingestible Osmotic Pill for In‐vivo Sampling of Gut Microbiome

July 2019 Authors: Hojatollah Rezaei Nejad, Bruno C. M. Oliveira, Aydin Sadeqi, Amin Dehkharghani, Ivanela Kondova Jan A. M. Langermans, Jeffrey S. Guasto, Saul Tzipori, Giovanni Widmer, Sameer R. Sonkusale Info: From Engineering and Nano Labs at Tufts University, and … more »

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Systematic sequencing of chloroplast transcript termini from Arabidopsis thaliana reveals >200 transcription initiation sites and the extensive imprints of RNA-binding proteins and secondary structures

April 2019 Authors: Benoît Castandet, Arnaud Germain, Amber M. Hotto, and David B. Stern Info: Researchers present a protocol called Terminome-Seq that they developed to catalog RNA transcript termini in chloroplast DNA of Arabidopsis thaliana. RNA-seq libraries are prepared for … more »

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